论文部分内容阅读
为观察ＨＸ－１号液保存狗肾脏效果，运用本地杂种狗２０只，用ＨＣ－ＷＣＵ液（对照组）和ＨＸ－１液（实验组）低温保存狗肾４８、７２小时后，行自体异位肾移植观察术后狗肾功能恢复及存活情况。结果显示：ＨＣ－ＷＣＵ液４８、７２小时组，术后血肌酐峰值为６４２．６０±１５８．６０μｍｏｌ／Ｌ及６８６．２０±１５４．０４μｍｏｌ／Ｌ，ＨＸ－１液４８、７２小时组术后血肌酐峰值为４４８．３２±３６．９μｍｏｌ／Ｌ及５２４．６０±１０９．３８μｍｏｌ／Ｌ；ＨＣ－ＷＣＵ液保存肾４８、７２小时移植存活率为８０％和４０％，ＨＸ－１液保存肾移植存活率为１００％和６０％；ＨＣ－ＷＣＵ液组死于肾衰的肾组织损害明显重于ＨＸ－１液，结果表明ＨＸ－１液对狗肾脏的保存效果优于ＨＣ－ＷＣＵ液，其有效保存时间可能达４８～２７小时。
In order to observe the effects of HX-1 fluid on the preservation of canine kidney, twenty dogs from local hybrid dogs were treated with HC-WCU solution (control group) and HX-1 fluid (experimental group) for 48 and 72 hours. Renal function recovery and survival of dogs after kidney transplantation. The results showed that the peak value of serum creatinine was 482.60 ± 158.60μmol / L and 686.20 ± 154.04μmol / L in HC-WCU 48 and 72 hours group, and 48 and 72 hours in HX-1 group Serum creatinine peak 448.32 ± 36.9μmol / L and 524.60 ± 109.38μmol / L; HC-WCU fluid preservation kidney 48, 72 hours graft survival rate of 80% and 40%, HX-1 fluid preservation of kidney The graft survival rate was 100% and 60% respectively. The damage of kidney tissue in HC-WCU solution group was significantly higher than that in HX-1 solution. The results showed that HX- The effective preservation time may reach 48 ~ 27 hours.