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本文对波阳县部分农村的经产妇8279人进行了生育情况及其子女先天性缺陷的回顾性调查。表明:年龄组越大,平均妊娠次数越多(1.2—6.9次);自然流产率为5.8%;人工流产率为4. 4%,其中最多的达8次;死胎死产率为1.4%;先天缺陷患者人数174名,占0.49%;先天性智力低下患者山区(0.45%)比平原(0.21%)出现率高。先天缺陷患者中,父母为近亲结婚的有44人,占25.28%;有阳性家族史的63人,占32.21%。提示先天性缺陷患者发病与遗传因素有关。
In this paper, 8279 pregnant women in some rural areas of Bo Yang County were retrospectively surveyed about their fertility status and their children’s congenital defects. The results showed that: the older the age group, the more the average number of pregnancies (1.2-6.9 times); spontaneous abortion rate was 5.8%; abortion rate was 4.4%, of which up to 8 times; stillbirth rate of 1.4%; The number of patients with congenital defects 174, accounting for 0.49%; mountain congenital mental retardation (0.45%) higher than plain (0.21%). Among the patients with congenital defects, 44 were married with relatives, accounting for 25.28%; 63 with positive family history, accounting for 32.21%. Tip congenital defects in patients with genetic factors.