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本文报道了宁夏盐池县马儿庄,改水8年防治地方性氟中毒,在水氟、氟斑牙、氟骨症患者症状与体征、尿氟、以及骨X线片骨密度、骨结构等方面的变化。水氟多次检测稳定在0.8mg/L。成人氟斑牙改水前后病损改变不大,而改水后出生的儿童,却基本不患氟斑牙或病损程度极轻。氟骨症患者的症状与体征明显减轻占52.8％。精选26例X线拍片动态随诊对比观察,骨密度、骨结构明显减轻占76.92％。连续8年尿氟检测,由改水前15.61mg/L,分别降至5.80、5.01、3.71、3.07mg/L,第一年下降幅度最大。除第6与第8年两个样本均值无显著性外(P>0.05),其他各年都有极显著性(P<0.01)。但该病区均值仍高于宁夏非病区正常上限2.60mg/L水平。
This article reports the Ma’erzhuang Yanchi County, Ningxia, water for 8 years to prevent and control endemic fluorosis, fluoride in water, dental fluorosis, skeletal fluorosis symptoms and signs, urine fluoride, and bone X-ray bone mineral density, bone structure Changes in the area. Multiple fluoride test stability at 0.8mg / L. Before and after the adult dental fluorosis to change the lesion did not change much, while the children born after the water change, but basically no dental fluorosis or minimal damage. Patients with skeletal fluorosis symptoms and signs significantly reduced 52.8%. Featured 26 cases of X-ray film dynamic follow-up comparison, bone mineral density, bone structure significantly reduced accounted for 76.92%. Urine fluoride test for 8 consecutive years, by the water before 15.61mg / L, respectively, dropped to 5.80,5.01,3.71,3.07 mg / L, the largest decline in the first year. Except for the mean of the two samples in the 6th and 8th years, there was no significant difference (P> 0.05), but all the other years were significant (P <0.01). However, the ward mean value is still higher than the normal upper limit of non-ward Ningxia 2.60mg / L level.