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在以往的临床实践中,血清ANA的检测一直被认为是一个重要的诊断工具,尤其对全身性风湿性疾病的诊断、治疗及估计预后方面都有其它项目所不能替代的优越性,随着这类疾病基础研究的深入,人们认识到,核抗原是多种成份的复合体,针对复合体中的不同抗原可产生多种抗体。依这些抗体的类型,可将全身性风湿性疾病分为若干相对独立的疾病,这些疾病的诊断、治疗及预后都有所不同。可提取的核抗原(ENA)是经一定流程提取的细胞核成份,可作为抗核抗体特异性分析的底
In previous clinical practice, the detection of serum ANA has always been considered as an important diagnostic tool, especially for the diagnosis, treatment and prognosis of systemic rheumatic diseases, there are other projects that can not be replaced with the superiority, with this In-depth studies of basic diseases, it is recognized that nuclear antigen is a complex of multiple components, for different antigens in the complex can produce a variety of antibodies. Depending on the type of antibody, systemic rheumatoid disease can be divided into a number of relatively independent diseases that differ in their diagnosis, treatment, and prognosis. Extractable nuclear antigen (ENA) is a nucleus extracted by a certain process and can be used as the end of specific analysis of antinuclear antibodies