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本文对340例正常临产孕妇,3例乙型肝炎孕妇及2例婴儿暴发型肝炎进行了调查研究。发现正常孕妇HBsAg阳性率为5.9％;23例HBsAg阳性孕妇的婴儿脐血HBsAg阳性率为8.7％;随访了15对母婴,有4对见母婴垂直传播,其中有一对为一个母亲先后生育2个婴儿均患暴发型肝炎死亡,该母作2例计,共为16例母亲,5个婴儿受HBV感染,垂直传播者达31.3％,初步研究结果表明HBV是否发生垂直传播与母血的eAg及Dane颗粒的存在密切相关,而与母乳喂养关系不大。作者对垂直传播率、影响垂直传播的因素、垂直传播的结果等进行了讨论。
In this paper, 340 cases of normal pregnant women, 3 cases of hepatitis B pregnant women and 2 cases of infant fulminant hepatitis were investigated. The positive rate of HBsAg in normal pregnant women was 5.9%. The positive rate of HBsAg in cord blood of 23 pregnant women with HBsAg positive was 8.7%. After 15 pairs of mother and infant were followed, there were 4 pairs of vertical transmission of mother to child, of which, one pair had one mother Two infants died of fulminant hepatitis, the mother of 2 cases, a total of 16 mothers, 5 infants infected by HBV, the vertical transmission of up to 31.3%, the preliminary results show that the vertical transmission of HBV and maternal eAg and Dane particles are closely related to the existence, but not with breastfeeding. The authors discuss the vertical transmission rate, the factors that affect vertical transmission, the vertical transmission results and so on.