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目的了解辽宁省腹泻症候群细菌病原谱构成,对临床诊断、治疗用药与预防突发公共卫生事件提供依据。方法对2012年-2016年辽宁省腹泻症候群临床患者粪便标本检测结果进行分析,了解病原谱构成情况。结果 1 307份样本中,检出7种细菌病原核酸242份,检出率为18.52%,混合感染占4.12%。致泻性大肠埃希菌47份(3.60%),非伤寒沙门菌33份(2.52%),志贺菌7份(0.54%),副溶血性弧菌119份(9.10%),嗜水气邻单胞菌28份(2.14%),类志贺邻单胞菌6份(0.46%),霍乱弧菌2份(0.15%)。结论构成辽宁省腹泻症候群细菌病原种类繁多,主要以副溶血性弧菌、致泻性大肠埃希菌为主。其中副溶血性弧菌是本地区主要的细菌感染病原。
Objective To understand the composition of the bacterial pathogenic spectrum of diarrhea syndrome in Liaoning Province and provide evidences for clinical diagnosis, treatment and prevention of public health emergencies. Methods The results of stool specimens from clinical patients of diarrhea syndrome in Liaoning Province from 2012 to 2016 were analyzed to understand the composition of the pathogenic spectrum. Results Of the 1 307 samples, 242 bacterial nucleic acid pathogens were detected, the detection rate was 18.52%, mixed infection accounted for 4.12%. 47 (3.60%) of diarrheal Escherichia coli, 33 (2.52%) of non-typhoid Salmonella, 7 (0.54%) of Shigella, 119 (9.10%) of Vibrio parahaemolyticus, 28 (2.14%) strains of Pseudomonas, 6 (0.46%) strains of Pseudomonas, and 2 (0.15%) strains of Vibrio cholera. Conclusions A large number of bacterial pathogens that constitute the diarrhea syndrome in Liaoning Province are mainly Vibrio parahaemolyticus and diarrheal Escherichia coli. Vibrio parahaemolyticus which is the main bacterial infection in the region.