基于树突状细胞的肝细胞癌免疫治疗研究进展

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肝细胞癌(HCC)是最常见的原发性肝癌,目前,免疫疗法已成为继手术治疗、放射治疗、化学治疗之后的第4种治疗HCC的手段.许多研究证明,免疫治疗可以提高机体的免疫功能,以减少HCC的复发和转移、延长患者生存期.树突状细胞(DC)是体内功能最强大的抗原提呈细胞,在机体的抗肿瘤免疫应答中发挥着重要作用.DC抗肿瘤疫苗、DC-细胞因子诱导的杀伤细胞细胞疗法、DC免疫治疗联用肝动脉化疗栓塞术和光动力疗法等以DC为基础的方式已成为HCC免疫治疗研究中的热点,并展现出良好的前景.笔者将对近几年基于树突状细胞的HCC免疫治疗的研究进展进行综述.
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