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荷瘤宿主对肿瘤的免疫反应低下,不能诱导有效的抗肿瘤免疫;器官移植时,由于供受体之间组织相容性复合物的不同,诱发移植排斥反应,往往导致移植器官功能丧失和器官死亡。利用辩证的逆向思维方法,将对器官移植不利的移植排斥反应引入恶性肿瘤的免疫治疗,可能是一条有希望的治疗途径。此设想在方法上有其可行性,而且类比大量的肿瘤免疫治疗和基因治疗的最新研究成果,此设想有可能取得预期的结果。
Tumor-bearing hosts have a low immune response to tumors and do not induce effective anti-tumor immunity. Organ transplantation, due to differences in histocompatibility complexes between receptors, induces graft rejection, often resulting in loss of organ function and organ transplantation. death. The use of dialectical reverse thinking methods to introduce an unfavorable transplant rejection of organ transplantation into the immunotherapy of malignant tumors may be a promising therapeutic approach. This idea has its methodological feasibility, and it is comparable to a large number of recent researches on tumor immunotherapy and gene therapy, and it is possible to achieve the desired results.