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母体之所以不排斥胎儿,以往认为由于子宫无免疫排斥能力、存在机械屏障或胎儿缺乏移植抗原。但近来研究表明:子宫内膜中可发生对移植物的排斥、蜕膜与滋养层之间并不存在机械屏障,甚至在胚泡种植前已具有移植抗原。母体对胎儿相关抗原虽能发生免疫反应,但在正常情况下并不排斥胚胎;看来控制母体免疫反应的主要机制是一种通过可溶性血清因子、局部释放激素、各种胎盘抗原
The reason why the mother does not exclude the fetus, the past that the uterus due to non-immune rejection, the existence of mechanical barriers or lack of fetal transplantation antigen. However, recent studies have shown that graft rejection can occur in the endometrium with no mechanical barrier between the decidua and the trophoblast, even with the transplantation of antigens prior to blastocyst implantation. Although the maternal immune response to fetal antigen, but under normal circumstances does not exclude the embryo; appears to control the maternal immune response is the main mechanism by a soluble serum factor, local release of hormones, a variety of placental antigen