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本文用119例大鼠,观察左心室壁内血管和结扎左冠状动脉后心壁内血管的变化。其中75例心脏经主动脉灌注20％中国墨汁明胶液后,作火棉胶切片;另外44例心脏直接固定,作石蜡幼片观察。大鼠左心室游离壁内血管类型与人及家兔基本相似。室间隔内毛细血管分布与家兔相似。左心室游离壁毛细血管数目为3,903±48条/mm~2,毛细血管与心肌纤维数目比例约为1:1。毛细血管互相吻合成网,其走行与心肌纤维方向一致。结扎大鼠左冠状脉后,左心室壁内血管变化可分为缺乏血管、血管密集和血管稀疏等三个阶段,其演变规律与修复过程相适应,并提示大鼠心肌梗塞后1～2天,侧支循环开始建立;3～7天,侧支循环逐渐丰富。与人类心肌梗塞和家兔心肌梗塞模型相比,大鼠心肌梗塞模型的血管自然演变过程较快,但规律是相似的。
In this paper, 119 rats were used to observe the changes of blood vessels in the wall of the left ventricular wall and the left coronary artery. Among them, 75 cases were infused with 20% Chinese ink gelatin solution through the aorta, and then cut into sponge gel slices. Another 44 cases of heart were directly fixed and observed for paraffin. Left ventricular free wall in rats with vascular type and human and rabbit basically similar. Capillary distribution within the interventricular septum and rabbit similar. The number of left ventricular free wall capillaries was 3,903 ± 48 / mm ~ 2, and the ratio of capillary to myocardial fibers was about 1: 1. Anastomosis of capillaries into a network, its line of travel and myocardial fibers in the same direction. Left ligation of the left coronary artery, left ventricular wall vascular changes can be divided into a lack of blood vessels, vascular dense and sparse blood vessels and other three stages, the evolution of law and repair process to adapt to and prompt 1 to 2 days after myocardial infarction in rats , Collateral circulation began to establish; 3 to 7 days, collateral circulation gradually enriched. Compared with human myocardial infarction and rabbit myocardial infarction model, the natural evolution of blood vessels in myocardial infarction model of rats is faster, but the laws are similar.