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目的:探讨血必净注射液治疗原发性腹膜炎(SBP)的临床价值。方法:回顾分析我科2008年3月～2010年2月以抗生素药物配伍静脉滴注血必净注射液治疗肝硬化合并SBP90例,并与常规治疗方法对照组78例对比。结果:治疗组总有效率92.22%明显高于对照组的80.77%,差异有统计学意义;两组治疗后谷丙转氨酶(ALT)、总胆红素(TBIL)值下降,血浆白蛋白(ALB)值上升,其中治疗组ALT、TBIL值下降明显,ALB值上升明显,两组改善程度比较,治疗组明显高于对照组,差异有统计学意义(P<0.01);治疗组治疗前腹水细菌培养阳性5例(5.56%),对照组3例(3.85%),包括大肠杆菌6株,肺炎克雷伯杆菌2株。治疗后腹水细菌培养阳性2例(2.22%),对照组1例(1.28%),包括大肠杆菌2株,肺炎克雷伯杆菌1株。差异均无有统计学意义(P>0.05)。结论:血必净注射液对疾病的症状减轻和促进机体器官功能的恢复有良好作用。因此,中西医结合方法治疗SBP效果良好,值得进一步推广使用。
Objective: To investigate the clinical value of Xuebijing injection in the treatment of primary peritonitis (SBP). Methods: A retrospective analysis of our department from March 2008 to February 2010 antibiotic drug compatibility with intravenous Xuebijing injection of cirrhosis combined with SBP 90 cases, and 78 cases compared with the conventional treatment of the control group. Results: The total effective rate of the treatment group was 92.22%, which was significantly higher than that of the control group (80.77%), the difference was statistically significant. The levels of ALT and TBIL decreased, ), The ALT and TBIL values of the treatment group decreased significantly, ALB value increased significantly, the improvement degree of the two groups was significantly higher than that of the control group, the difference was statistically significant (P <0.01); the treatment group before treatment ascites bacteria There were 5 positive cases (5.56%) and 3 control cases (3.85%), including 6 strains of Escherichia coli and 2 strains of Klebsiella pneumoniae. After treatment, bacterial culture in ascites was positive in 2 cases (2.22%) and in control group in 1 case (1.28%), including 2 strains of Escherichia coli and 1 strain of Klebsiella pneumoniae. The difference was not statistically significant (P> 0.05). Conclusion: Xuebijing Injection can relieve the symptoms of the disease and promote the recovery of organ function. Therefore, the combination of traditional Chinese and Western medicine treatment of SBP works well, it is worth further promotion.