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[目的]观察奥美拉唑联合心得安、硝苯地平治疗肝源性溃疡的疗效。[方法]肝源性溃疡42例,联合治疗组21例给予奥美拉唑联合心得安和硝苯地平口服,对照组单纯用奥美拉唑,治疗4周为1个疗程。[结果]联合治疗组的有效率为95.2%(20/21),对照组为80.9%(17/21),两组比较差异有统计学意义(P﹤0.05)。[结论]奥美拉唑联合心得安、硝苯地平对肝源性溃疡的疗效优于单纯抑酸治疗。
[Objective] To observe the curative effect of omeprazole and propranolol and nifedipine in treating liver-derived ulcer. [Method] Forty-two patients with liver-derived ulcer were treated with omeprazole and propranolol and nifedipine orally in combination therapy group. Omeprazole alone was used in the control group. One course of treatment was 4 weeks. [Results] The effective rate of the combined treatment group was 95.2% (20/21) and that of the control group was 80.9% (17/21). The difference between the two groups was statistically significant (P <0.05). [Conclusion] Omeprazole combined with propranolol and nifedipine is better than pure acid-suppressing treatment for liver-derived ulcer.