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目的了解杭州市在全民食盐加碘后城乡不同孕期妊娠妇女碘营养状况,为妊娠妇女科学补碘提供依据。方法杭州市12个县(市、区)各抽取一个调查点,各调查点选择100名不同孕期的妊娠妇女。采集其家庭盐样和尿样,分别采用硫代硫酸钠直接滴定法和酸消化砷-铈接触法进行盐碘和尿碘检测。结果杭州市共检测妊娠妇女家庭盐碘1172份,盐碘中位数为28.7 mg/kg,碘盐覆盖率为96.47%,合格碘盐食用率为94.02%。检测尿样1172份,尿碘中位数值为125.00μg/L,其中城区、郊区和农村妊娠妇女尿碘中位数分别为132.00、121.90和118.90μg/L,3组间尿碘浓度差异有统计学意义(P<0.01)。3组妊娠妇女尿碘浓度<150μg/L分别为58.95%、71.50%和65.14%。孕早、中、晚期孕妇尿碘中位数分别是127.00、127.65和122.05μg/L,其中各期孕妇尿碘<150μg/L的比率分别为58.87%、64.52%和66.04%,不同孕期之间尿碘<150μg/L的比例差异无统计学意义(P>0.05)。结论杭州市城乡部分不同孕期妊娠妇女碘营养水平仍处于碘缺乏状况,建议孕妇除坚持食用合格碘盐外,还应每周适当食用富碘的海产品,同时加强对妊娠妇女的碘营养监测。
Objective To understand the status of iodine nutrition in pregnant women in different pregnant and urban areas of Hangzhou after iodification of common salt in Hangzhou and provide the basis for scientific iodine supplementation in pregnant women. Methods Twelve counties (cities and districts) in Hangzhou collected one investigation point and selected 100 pregnant women of different pregnancy from each survey point. Salt samples and urine samples were collected from their families. Salt iodine and urine iodine were detected by direct titration with sodium thiosulfate and acid-arsenic-cerium contact method respectively. Results A total of 1172 salt iodine in pregnant women were detected in Hangzhou. The median of salt iodine was 28.7 mg / kg, the coverage of iodized salt was 96.47%, and the qualified iodized salt was 94.02%. Urinary iodine was detected in 1172 samples with a median urinary iodine value of 125.00 μg / L. The urinary iodine median of pregnant women in urban, suburban and rural areas were 132.00, 121.90 and 118.90 μg / L, respectively Significance (P <0.01). The urinary iodine concentrations in three groups of pregnant women were 58.95%, 71.50% and 65.14%, respectively. The median urinary iodine of pregnant women in the early, middle and late stages of pregnancy was 127.00, 127.65 and 122.05 μg / L, respectively, and the urinary iodine <150 μg / L in each stage of pregnancy was 58.87%, 64.52% and 66.04%, respectively. The urinary iodine <150μg / L was no significant difference (P> 0.05). Conclusions Iodine nutritional status of pregnant women in urban and rural areas in different stages of pregnancy is still in the state of iodine deficiency. It is suggested that pregnant women should eat iodine-rich seafood once a week in addition to adhering to qualified iodized salt, and strengthen monitoring of iodine nutrition in pregnant women.