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目的观察血管紧张素Ⅱ受体拮抗剂(缬沙坦)治疗慢性充血性心力衰竭的疗效。方法选择160例慢性充血性心力衰竭患者随机分为治疗组和对照组各80例,两组均给予常规抗心力衰竭治疗,治疗组在常规治疗基础上加用缬沙坦80~160mg,口服,1次/d,连用12周,观察治疗前后两组患者临床症状和心功能的改善情况。结果治疗组总有效率为96.3%,对照组总有效率为77.5%,两组比较有统计学意义(P<0.05)。结论缬沙坦能提高慢性充血性心力衰竭临床疗效。
Objective To observe the effect of angiotensin Ⅱ receptor antagonist (valsartan) on chronic congestive heart failure. Methods 160 patients with chronic congestive heart failure were randomly divided into treatment group and control group of 80 cases, both groups were given conventional anti-heart failure treatment, the treatment group on the basis of conventional treatment with valsartan 80 ~ 160mg, oral, 1 / d, once every 12 weeks to observe the improvement of clinical symptoms and cardiac function in both groups before and after treatment. Results The total effective rate was 96.3% in the treatment group and 77.5% in the control group, with statistical significance (P <0.05). Conclusion Valsartan can improve the clinical efficacy of chronic congestive heart failure.