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目的观察宫内节育器(intrauterine contraceptive device,IUD)吉妮柔适与TCu380的临床避孕效果。方法采用对比性研究,选取2007年1月至2008年1月在建湖县计划生育指导站自愿要求放置IUD、身体健康且无置器禁忌证的已婚育龄妇女800例,用知情选择与随机放置相结合的方法分成两组(各400例),分别放置吉妮柔适IUD和TCu380IUD,并进行12个月定期随访(术后1、3、6、12个月)。结果吉妮柔适IUD的脱落率(伴下移)和因症取出率显著低于TCu380IUD,而累积续用率显著高于TCu380IUD(P<0.05)。结论吉妮柔适IUD避孕效果明显,具有脱落率低、不良反应少、累积续用率高的优点,可在临床推广使用。
Objective To observe the clinical contraceptive effect of gefitinib and TCu380 in intrauterine contraceptive device (IUD). Methods A comparative study was conducted to select 800 married women of childbearing age who volunteered to place IUD, healthy and without contraindications in Jianhu County Family Planning Supervisory Station from January 2007 to January 2008. With informed choice and randomized Place the combination of methods are divided into two groups (400 cases each), were placed Gently soft IUD and TCu380IUD, and 12-month follow-up (1,3,6,12 months after surgery). Results The rate of exfoliation (accompanied with downwards) and the rate of removal due to gefitinib IUD was significantly lower than that of TCu380IUD, and the cumulative follow-up rate was significantly higher than that of TCu380IUD (P <0.05). Conclusions Gentle soft IUD contraceptive effect is obvious, with a low rate of excretion, fewer adverse reactions, the cumulative high rate of use of the advantages of clinical use.