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目的了解传统隔离策略下传染病医院肝病内科医院感染发病基本特征。方法前瞻性调查2007年1月-2008年12月某三级甲等传染病专科教学医院肝病内科医院感染发生率。结果共调查住院患者4343例,医院感染394例,发病密度为3.030‰,发病率为9.1%;医院感染发病例次数457例次,例次发病密度为3.515‰,例次发病率为10.5%;常见医院感染发病部位依次为:原发性腹膜炎、血流感染、上呼吸道感染和下呼吸道感染,分别占22.5%、19.9%、19.7%及16.6%;医院内下呼吸道感染死亡和血流感染死亡最多;重型肝炎病区的医院感染发生强度最高,为5.02‰,其中医院内血流感染、下呼吸道感染例次发病强度分别为1.65‰、1.08‰,为全院之最。结论传统隔离策略下传染病医院肝病内科医院感染的分布以呼吸道感染、原发性细菌性腹膜炎和血流感染为主,医院内下呼吸道感染和血流感染的转归最为严重。
Objective To understand the basic characteristics of the morbidity and mortality of infectious liver disease hospital in the traditional isolation strategy. Methods A prospective survey was conducted to investigate the prevalence of liver infection in a liver disease hospital from January 2007 to December 2008 in a class III A infectious disease specialist teaching hospital. Results A total of 4343 inpatients were hospitalized, 394 were hospitalized, with an incidence of 3.030 ‰ and a prevalence of 9.1%. The incidence of nosocomial infections was 457, with an incidence of 3.515 ‰ and an incidence of 10.5%, respectively. The incidences of common nosocomial infections were as follows: primary peritonitis, bloodstream infection, upper respiratory tract infection and lower respiratory tract infection, accounting for 22.5%, 19.9%, 19.7% and 16.6% respectively; death from lower respiratory tract infection and death from bloodstream infection in the hospital The incidence of nosocomial infections in severe hepatitis wards was the highest at 5.02 ‰, of which the incidence of bloodstream infections and lower respiratory tract infections in hospitals was 1.65 ‰ and 1.08 ‰, respectively, the highest among all the hospitals. Conclusion The prevalence of respiratory tract infection, primary bacterial peritonitis and bloodstream infection in the hospital with infectious liver disease in the traditional isolation strategy is the most serious. The lower respiratory tract infection and bloodstream infection in the hospital are the most serious.