论文部分内容阅读
目的应用光学相干断层成像技术评价新型国产冠状动脉雷帕霉素药物洗脱支架(BUMA)置入后内膜覆盖。方法入选22例冠状动脉造影提示为原发冠状动脉病变需置入支架的冠心病患者,随机分为BUMA组(n=15)和对照组Endeavor组(n=7),术后9个月行光学相干断层成像检查。结果 BUMA组平均内膜增殖厚度显著小于Endeavor组(0.220±0.140mm对0.269±0.207mm,P<0.001);BUMA组无内膜覆盖百分率显著低于Endeavor组(5.65%对6.56%,P<0.001);BUMA组支架内管腔面积丢失显著小于Endeavor组有统计学差异[(34.87±11.50)%对(40.82±18.53)%,P=0.025]。结论冠心病患者置入国产新型BUMA药物洗脱支架具有良好的安全性和有效性。
Objective To evaluate the application of optical coherence tomography in the evaluation of intimal coverage after implantation of a new domestic coronary rapamycin-eluting stent (BUMA). Methods Twenty-two patients with coronary artery disease who underwent coronary angiography as the primary coronary artery lesion were enrolled in the study. They were randomly divided into BUMA group (n = 15) and control group Endeavor group (n = 7) Optical coherence tomography examination. Results The average thickness of intimal hyperplasia in BUMA group was significantly lower than that in Endeavor group (0.220 ± 0.140mm vs 0.269 ± 0.207mm, P <0.001). The percentage of intima coverage in BUMA group was significantly lower than that in Endeavor group (5.65% vs 6.56%, P <0.001) ). The lumen area loss in BUMA group was significantly smaller than that in Endeavor group [(34.87 ± 11.50)% vs (40.82 ± 18.53)%, P = 0.025]. Conclusion Coronary heart disease patients with domestic new BUMA drug-eluting stent has good safety and effectiveness.