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目的探讨连续性血液净化(CBP)在感染性休克致急性肾功能衰竭(ARF)中的临床疗效。方法 33例感染性休克致急性肾功能衰竭患者,给予连续性血液净化,同时治疗原发病,纠正水电解质酸碱平衡,积极抗休克治疗、控制感染,加强营养支持治疗,观察治疗前及治疗后7、15、30 d时血尿素氮(BUN)、肌酐(Cr)的变化及其转归。结果 33例中生存15例,死亡18例。死亡原因多因为多器官功能衰竭。结论 CBP能改善老年感染性休克所致ARF的BUN、Cr表达水平,但是对患者致死率无明显改善。
Objective To investigate the clinical efficacy of continuous blood purification (CBP) in septic shock-induced acute renal failure (ARF). Methods Thirty-three patients with acute renal failure caused by septic shock were treated with continuous blood purification, while treating the primary disease, correcting acid-base balance of water and electrolyte, actively treating with anti-shock, controlling infection and strengthening nutrition supportive therapy. Changes of blood urea nitrogen (BUN), creatinine (Cr) and their prognosis at 7, 15 and 30 days after operation. Results 33 cases of survival in 15 cases, 18 cases of death. Many causes of death because of multiple organ failure. Conclusion CBP can improve the expression of BUN and Cr in ARF induced by septic shock in elderly patients, but there is no significant improvement in the lethality of patients.