【摘 要】
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Dear Editor,The anti-proliferative protein Tob belongs to the Tob/BTG family (Matsuda et al., 2001) and plays important roles in cell proliferation, embryonic d
【机 构】
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State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China“,”Colle
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Dear Editor,The anti-proliferative protein Tob belongs to the Tob/BTG family (Matsuda et al., 2001) and plays important roles in cell proliferation, embryonic development, cellular differentiation, cancer suppression, and apoptosis (Matsuda et al., 2001;Iwanaga et al., 2003;Ito et al., 2005;Jia and Meng, 2007;Mauxion et al.,2009;Winkler, 2010).The anti-apoptotic and pro-survival effects of Tob may provide a tumor escape mechanism against chemo-and radiation therapies (Suzuki et al., 2012).
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