【摘 要】
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Dear Editor,Altemative splicing (AS) is a post-transcriptional process that can add complexity to proteome greatly by producing multiple different mature transc
【机 构】
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Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Scienc
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Dear Editor,Altemative splicing (AS) is a post-transcriptional process that can add complexity to proteome greatly by producing multiple different mature transcripts from the same pre-RNA (Black, 2003).Ever since its discovery, multiple kinds of different AS types have been identified, for example, exon skipping (or cassette exon), intron retention, alteative 3/5 splice site (SS) and so on (Wang et al., 2008).Among them, the exon skipping event is expected to be the most abundant (Black, 2003).By applying different kinds of large scale data,such as exon array and EST, lots of progresses have been made.Recently, with the development of high throughput RNA-sequencing technology, our knowledge about AS has been further exploded (Wang et al., 2008).
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