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41例急性淋巴细胞白血病患儿染色体进行研究，异常核型检出率为76％。发现急淋患儿染色体结构异常可视为预后不佳的标志，而正常二倍体核型及超二倍体核型急淋患儿则预后较好。还对其中10例急淋患儿核型进行动态观察，提示细胞遗传学研究可作为急淋患儿病情评估和预后判断的重要监测指标。
41 cases of children with acute lymphoblastic leukemia chromosome research, the detection rate of abnormal karyotype was 76%. Found that children with acute lymph node chromosome abnormalities can be regarded as a sign of poor prognosis, and normal diploid karyotype and hyperdiploid karyotype acute lymphocyte prognosis is better. The karyotypes of 10 children with acute lymphocytic leukemia were also observed dynamically, which suggested that cytogenetics could be used as an important indicator of disease assessment and prognosis in children with acute lymphocytic leukemia.