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为研究血清超氧化物歧化酶（ＳＯＤ）清除超氧自由基的活性与年龄的定量关系，利用电子自旋共振（ＥＳＲ）谱仪测量４０例健康人。结果表示：①随着年龄的增长，人体血清ＳＯＤ活性逐渐下降；ＳＯＤ活性（Ｙ）与年龄（ｘ）呈显著负相关，ｒ＝－０４１；②经线性最小二乘拟合，Ｙ＝２０９０４－０５２ｘ；③将４０例按年龄分成幼年、青年、中青年、中老年４个组：其ＳＯＤ均值（Ｕ／Ｌ）分别为２０６２５±２４６１，１９００４±２２５５，１９６８８±２５５４，１６６３０±１８６８。经修正的ｔ检验判明，只有幼年组与中老年组之间存在显著差异（Ｐ＜００１）。表明采用ＥＳＲ波谱技术所得结果与其他方法基本一致。
In order to study the quantitative relationship between serum superoxide dismutase (SOD) scavenging superoxide radical activity and age, 40 healthy subjects were measured by electron spin resonance (ESR) spectroscopy. The results showed that: (1) With the increase of age, the activity of SOD in human serum gradually decreased; the activity of SOD (Y) was negatively correlated with age (x), r = -041; ② After linear least squares fitting, 209 04-0 52x; 40 cases were divided into four groups according to age: young, young, middle-aged, middle-aged and old: the SOD mean (U / L) were 206.25 ± 24.61 and 190.04 ± 2255, 19688 ± 2554, 16630 ± 1868. The revised t test showed that there was only significant difference between the young group and the middle-aged group (P <001). It shows that the results obtained by ESR spectroscopy are basically the same as other methods.