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本文报道46例肝硬化患者口服葡萄糖胰岛素释放试验的结果,并与18名正常人和18名原发性糖尿病患者比较。肝硬化患者糖耐量减低者28例(60.9％),其中29例(43.5％)呈糖尿病型耐量曲线。胰岛素释放高峰值在服糖后2h;释放过多和分泌延迟者32例(69.6％),降低者4例(8.7％)。20例肝源性糖尿病患者的胰岛素释放指数明显高于原发性糖尿患者。笔者认为血浆胰岛素和胰岛素释放指数测定对鉴别这两种类型的糖尿病有很大价值。
This article reports the results of oral glucose insulin release test in 46 patients with cirrhosis and compared with 18 normal subjects and 18 patients with primary diabetes. 28 patients (60.9%) with impaired glucose tolerance in patients with cirrhosis, of which 29 patients (43.5%) showed diabetes tolerance curve. The peak of insulin release was 2 hours after oral administration of sugar. 32 cases (69.6%) had delayed release and delayed release, while 4 cases (8.7%) had delayed release. Insulin release index of 20 patients with liver-derived diabetes was significantly higher than that of primary diabetes patients. The author believes that plasma insulin and insulin release index determination of the identification of these two types of diabetes have great value.