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根据一些药物经紫外光照射后发出的荧光强度与药物浓度有关这一原理,设计了一种能在位连续监测血药浓度的光纤传感器,该传感器采用了Y型光纤探头,可直接插入血液中进行测量。在探头端面处加了一细长的自聚焦透镜,可以提高探头的集光本领。仪器用计算机控制步进电机,使色散元件的转动与荧光信号的采集一一对应,从而可在屏幕上显示出波长-荧光强度-时间的三参数荧光光谱,提高了可视性。该仪器的检测极限可达μg/ml数量级,并可广泛应用于其它测量领域。
Based on the principle that some drugs emit fluorescence intensity and drug concentration after ultraviolet light irradiation, an optical fiber sensor capable of continuously monitoring blood concentration in position is designed. The sensor uses a Y-type optical fiber probe and can be directly inserted into the blood Make measurements. In the probe end plus a slender self-focusing lens, you can improve the collecting skills of the probe. The instrument uses a computer to control the stepping motor so that the rotation of the dispersive element corresponds to the collection of the fluorescence signal, so that the three-parameter fluorescence spectrum of wavelength-fluorescence intensity-time can be displayed on the screen to improve the visibility. The limits of detection of the instrument up to μg / ml orders of magnitude, and can be widely used in other measurement areas.