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本文观察22例重度黄疸肝炎病人黄疸高峰期的超微结构改变,并与其中14例的黄疸消退期二次肝穿标本进行对比,同时观察了应用凉血活血中药治疗本病的效果。结果显示本病超微结构改变包括:1.肝窦和狄氏腔的狭窄及阻塞,并因此导致肝微循环障碍;2.胆汁淤积;3.肝细胞损伤;4.淋巴细胞浸润及胶原纤维增生。对比观察证实肝微循环障碍在本病发生和发展过程中起重要作用,因此治疗本病宜从活血化瘀入手。
This article observed 22 cases of severe jaundice hepatitis patients with jaundice ultrastructure changes and with 14 cases of jaundice extinction of the second liver transcripts were compared at the same time observed the application of cooling blood and activating blood medicine in the treatment of this disease. The results showed that the ultrastructural changes of the disease include: 1. Stenosis and obstruction of hepatic sinusoid and discoid cavity, and thus lead to liver microcirculation disorders; 2. Cholestasis; 3. Hepatocyte injury; 4. Lymphocyte infiltration and collagen fibers Hyperplasia. Comparative observation confirmed liver and microcirculation disorders play an important role in the occurrence and development of this disease, so the treatment of this disease should start with blood circulation.