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目的： 探索宫腔灌注顺铂治疗功能失调性子宫出血（功血）的疗效． 方法： 选１０例无生育要求的功血患者，将１０ｍ ｇ 顺铂稀释至１０ ｍ Ｌ，每次注入宫腔６ ｍ Ｌ～８ ｍ Ｌ， ４次为一疗程． 结果： １０例患者中６例既往月经过多者治疗后月经量明显减少；４例经期延长者治疗后经期变为正常． ６例复查宫内膜病理变化，其中４例子宫内膜单纯增生过长，１例囊腺样增生及１例腺瘤样增生者，治疗一个疗程后均转变为分泌期内膜．结论： 宫腔灌注顺铂可逆转宫内膜病理变化，减少子宫出血量及缩短出血时间．
Objective: To explore the efficacy of intrauterine perfusion of cisplatin in the treatment of dysfunctional uterine bleeding (dysfunctional uterine bleeding). Methods: Ten patients with dysfunctional uterine bleeding were selected and 10m g of cisplatin was diluted to 10 mL. Each time they were injected into the uterine cavity, 6 mL to 8 mL, four times a course of treatment. Results: Six of 10 patients had significantly lower menstrual flow after the previous menstruation. The menstruation of 4 patients with prolonged menstruation became normal. 6 cases of endometrial pathological changes were reviewed, of which 4 cases of endometrial hyperplasia was too long, 1 cases of cystoid hyperplasia and 1 cases of adenoid hyperplasia, after a course of treatment were transformed into secretory endometrium. Conclusion: Intrauterine infusion of cisplatin can reverse endometrial pathological changes, reduce the amount of uterine bleeding and shorten the bleeding time.