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可能由于中耳对抗生素的吸收较差,加之慢性中耳炎常见的致病菌,文献报道19～69%的假单胞菌属对常用的抗生素又有耐药性,故对慢性中耳炎的抗生素治疗难以取得满意的效果。基于1985年Fujimaki等用口服盐酸环丙氟哌酸200mgTid,治疗慢性中耳炎取得显著效果的报道,并通过不同浓度的环丙氟哌酸盐水滴耳剂的研究,选用250mg/ml浓度的盐酸环丙氟哌酸盐水和庆大霉素肌肉注射作对照,治疗慢性中耳炎。患者条件要求是18岁以上成
Probably due to poor absorption of antibiotics in the middle ear, and common pathogenic bacteria in chronic otitis media, 19 ~ 69% of the reported Pseudomonas strains are resistant to commonly used antibiotics, so antibiotic treatment of chronic otitis media is difficult Achieve satisfactory results. Based on a 1985 report by Fujimaki et al. Of oral ciprofloxacin hydrochloride 200 mg Tid for the treatment of chronic otitis media, the remarkable effect was reported. Ciprofloxacin water drops of different concentrations were used to study the erectile effects of 250 mg / ml cyclosporine hydrochloride Norfloxacin water and gentamicin intramuscular injection as a control, the treatment of chronic otitis media. Patient requirements are over 18 years of age