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[目的]探讨类风湿关节炎患者行全膝关节置换术后深静脉血栓的发病率及溶栓效果研究。[方法]2009年2月～2011年5月手术治疗类风湿关节炎24例,其中男性4例,女性20例;年龄29～74岁,平均58.2岁。双膝关节置换术6例(分两次手术),6例行左膝关节置换术,12例行右膝关节置换术。全膝关节置换术后行下肢深静脉造影诊断是否有深静脉血栓形成,术后深静脉血栓形成患者使用系统性溶栓治疗。[结果]深静脉造影术后,类风湿关节炎行全膝置换术后深静脉发生率为26.7%;系统性溶栓后,临床有效率为100%。分别在术后3、6个月随访两次。[结论]类风湿关节炎行全膝关节置换术后深静脉血栓发生率不低,值得在今后的临床工作中注意;下肢深静脉造影是关节置换术后诊断深静脉血栓形成的必要手段。
[Objective] To investigate the incidence and the thrombolytic effect of deep vein thrombosis after total knee arthroplasty in patients with rheumatoid arthritis. [Methods] From February 2009 to May 2011, 24 cases of rheumatoid arthritis were treated by surgery, including 4 males and 20 females. The average age was from 29 to 74 years with an average of 58.2 years. Double knee replacement surgery in 6 cases (divided into two operations), 6 cases of left knee replacement, 12 cases of right knee replacement. After total knee arthroplasty, deep vein thrombosis was performed to diagnose whether there was deep vein thrombosis. Patients with postoperative deep vein thrombosis were treated with systemic thrombolysis. [Results] After deep venography, the incidence of deep veins after total knee replacement in rheumatoid arthritis was 26.7%. After systemic thrombolysis, the clinical effective rate was 100%. They were followed up for 3 and 6 months respectively. [Conclusion] The incidence of deep venous thrombosis after total knee arthroplasty in rheumatoid arthritis is not low, which is worth noting in the future clinical work. Deep venous angiography of lower extremities is a necessary measure to diagnose deep venous thrombosis after arthroplasty.