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目的分析评价甲钴胺与莫沙必利联合治疗糖尿病性胃轻瘫的疗效。方法将85例糖尿病性胃轻瘫患者随机分为治疗组和对照组。两组患者在性别、年龄、症状等方面有可比性。在常规降糖治疗的同时,治疗组应用莫沙必利联合甲钴胺进行治疗,对照组只用莫沙必利,疗程4周,疗程结束后比较两组的疗效及复发率。结果治疗组的有效率(92.68%)大于对照组的有效率(72.73%),差异有统计学意义(P<0.05);疗程结束后治疗组的复发率(36.58%)低于对照组(70.45%),差异有统计学意义(P<0.05)。两组均未见不良反应。结论甲钴胺与莫沙必利联合治疗糖尿病性胃轻瘫患者胃效果显著,优于单用莫沙必利。
Objective To evaluate the efficacy of combination of mecobalamin and mosapride in the treatment of diabetic gastroparesis. Methods 85 cases of diabetic gastroparesis were randomly divided into treatment group and control group. Two groups of patients in gender, age, symptoms and other aspects of comparability. At the same time of regular hypoglycemic treatment, the treatment group was treated with mosapride combined with mecobalamin, the control group only with mosapride, the course of treatment for 4 weeks after the end of treatment, the curative effect and recurrence rate were compared. Results The effective rate (92.68%) in the treatment group was significantly higher than that in the control group (72.73%), the difference was statistically significant (P <0.05). The recurrence rate was 36.58% in the treatment group after treatment was lower than that in the control group %), The difference was statistically significant (P <0.05). No adverse reactions were seen in both groups. Conclusion Mecobalamin combined with mosapride in patients with diabetic gastroparesis stomach effect is significant, superior to mosapride alone.