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目的阴道超声观察药物对人流术后子宫内膜修复周期的影响,探讨人工流产术后即时应用药物修复子宫内膜的必要性和可行性。方法选取2010年10月~2013年10月到本院进行两次及以上的人工流产患者206例,随机分成两组,每组103例。一组未服用药物为观察组,另一组口服避孕药为对照组。连续服药3周,观察子宫内膜厚度,观察两组月经量和不良反应发生情况。对照组患者在给药后偶可出现恶心、呕吐、头昏以及乳腺小叶增生等不良反应。结果对照组患者的子宫内膜均显示增厚,观察组患者的子宫内膜未完全增厚,与对照组相比,差异有统计学意义。观察组患者经治疗后,月经量也比治疗前明显增多,两组不良反应比较差异无统计学意义(P>0.05)。结论人工流产后立即经药物治疗能更快地修复子宫内膜,可作为人工流产术后子宫内膜修复的常规治疗。人工流产术后未经药物治疗的患者子宫内膜修复缓慢。
Objective To observe the effect of drugs on the period of endometrial repair after abortion, and to explore the necessity and feasibility of immediate application of drugs to repair endometrium after artificial abortion. Methods Totally 206 induced abortion patients who visited our hospital from October 2010 to October 2013 were randomly divided into two groups (n = 103 in each group). One group did not take drugs as the observation group and the other group as the control group. Take 3 consecutive weeks of medication, observe the thickness of the endometrium, observe the menstrual flow and adverse reactions in both groups. Patients in the control group even after administration may appear nausea, vomiting, dizziness and lobular hyperplasia and other adverse reactions. Results The control group patients showed thickening of the endometrium, endometrial thickening of the observation group patients, compared with the control group, the difference was statistically significant. The observation group patients after treatment, menstrual flow than before treatment was significantly increased, the two groups showed no significant difference in adverse reactions (P> 0.05). Conclusion The medical treatment of the abortion immediately after the abortion can repair the endometrium more quickly, which can be used as a routine treatment of endometrial repair after induced abortion. Endometrial repair is slow in untreated patients after induced abortion.