论文部分内容阅读
采用五肽胃泌素刺激试验对47例慢性萎缩性胃炎（CAG）进行胃液分析，并和49例慢性浅表性胃炎（CSG）进行对照，以测定CAG患者胃酸分泌的储备功能。结果：①CAG患者BAO、MAO和PAO均明显降低，平均壁细胞数4．9亿个。非分泌状态的储备壁细胞3．7亿个。CSG平均壁细胞数8．1亿个，6．5亿个是非分泌状态的储备壁细胞，大约是CAG的1．7倍，表明CAG胃泌酸储备功能降低。②CGG患者胃液分泌量明显减少，但空腹胃液及五肽胃泌素刺激后胃液［H+］和CSG相同，说明CAG现存壁细胞的功能正常。③五肽胃泌素刺激后［H+］及胃液分泌量在CAG和CSG均明显增加，说明H+分泌速率代偿性增强，因此胃泌酸储备功能包括二个方面即壁细胞的数量和壁细胞对H+的分泌速率。
Forty-seven patients with chronic atrophic gastritis (CAG) underwent gastric juice analysis by pentagastrin stimulation test and compared with 49 patients with chronic superficial gastritis (CSG) to determine the gastric acid secretion reserve function in CAG patients. Results: ①CAG patients BAO, MAO and PAO were significantly lower, the average number of 490 cells wall cells. The number of non-secreted reserve parietal cells is 370 million. The average number of CSG cells in the CSG was 810 million, with 650 million non-secretory parietal cells, about 1.7-fold greater than CAG, indicating a reduction of gastrocnemius function in CAG. ②GGG gastric juice secretion decreased significantly, but after fasting gastric juice and pentagastrin stimulation of gastric juice [H +] and CSG the same, indicating that CAG existing parietal cells function properly. ③ pentagastrin stimulation [H +] and gastric secretion in CAG and CSG were significantly increased, indicating that H + secretion rate compensatory increase, so gastrin storage function includes two aspects of the number of parietal cells and parietal cells Secretion rate of H +.