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确诊内脏利什曼病(黑热病),需要证明在器官抽吸物中存在利什曼原虫。本文作者进行了前瞻性研究,旨在评定一种浸了利什曼原虫抗原的硝化纤维试纸在检测针对利什曼原虫抗原K39的抗体时,所具有的诊断价值。这是一种无创伤性的、适于现场诊断的试验。K39存在于全世界各种能引起内脏感染的利什曼原虫株的无鞭毛体中。
Diagnosis of visceral leishmaniasis (kala-azar) requires proof of the presence of Leishmania in the organ aspirate. The authors conducted a prospective study to assess the diagnostic value of a nitrocellulose paper impregnated with Leishmania antigen in the detection of antibodies to Leishmania antigen K39. This is a non-invasive test that is suitable for on-site diagnostics. K39 is present in the amastigotes of various Leishmania strains that cause visceral infections worldwide.