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为确定普通光镜检查尿红细胞形态是否准确，采用双盲法对经肾活检证实的５２例肾小球疾病及４０例非肾小球疾病尿样用在普通光镜下降低其聚光镜强度方法，在暗视野中观察尿畸形红细胞形态。当血尿病人的尿畸形红细胞≥７０％时，诊断为肾小球性血尿，敏感性９２％，特异性１００％。此法操作简便，准确性高，有较强的临床实用价值。
52 cases of glomerular disease confirmed by renal biopsy and 40 cases of non-glomerular disease were examined by double blind method to reduce the intensity of their condenser under ordinary light microscope. Urinary malformations of red blood cells were observed in dark field. When the urine of patients with urinary malformations of red blood cells ≥ 70%, the diagnosis of glomerular hematuria, 92% sensitivity and specificity of 100%. This method is simple, high accuracy, strong clinical practical value.