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目的探讨慢性充血性心力衰竭(CHF)患者窦性心率震荡(HRT)与心功能程度的关系。方法慢性心衰患者(CHF组)85例,全部病例按纽约心脏病协会(NYHA)心功能分级,分为轻度CHF组(心功能Ⅱ级)45例和重度CHF组(心功能Ⅲ～Ⅳ级)40例。另选同期心功能正常的42例作为对照组。所有入选者均接受24h动态心电图检查,分别计算窦性心率震荡的初始值(TO)、震荡斜率(TS),并进行统计学分析。结果3组的TO均值比较,重度CHF组与对照组比较差异有统计学意义(P<0.01);轻度CHF组与对照组比较差异有统计学意义(P<0.05);3组间的TS均值组间两两比较差异均有统计学意义(P<0.01)。结论伴随CHF患者程度加重,HRT现象明显变钝减弱,其变化可能与自主神经的变化有关。
Objective To investigate the relationship between sinus rhythm heart rate (HRT) and cardiac function in patients with chronic congestive heart failure (CHF). Methods Totally 85 patients with chronic heart failure (CHF) were enrolled in this study. All patients were divided into three groups based on the New York Heart Association (NYHA) cardiac function classification: mild CHF group (heart function grade Ⅱ) and severe CHF group (cardiac function Ⅲ ~ Ⅳ Grade) 40 cases. Another 42 cases of normal cardiac function of the same period as a control group. All participants underwent 24-hour Holter monitoring, and the initial values of TO and TS were calculated and statistically analyzed. Results There was significant difference between TO group and control group in CHF group (P <0.01). There was significant difference between mild CHF group and control group (P <0.05) There was significant difference between the mean groups (P <0.01). Conclusions With the severity of CHF patients, the HRT phenomenon becomes blunt and blunted, which may be related to the changes of autonomic nerve.