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本文介绍了新近Scheuer提出的慢性肝炎病理分级、分期标准,为与国内分型标准相对比,我们用二个标准观察了我院10年中316例慢性肝炎肝穿切片,探讨了52例乙肝病变活动性与病毒复制的关系,并分析了10例2次肝穿的病变转化。结果表明,(1)Scheuer分类的病变分级标准能较好地反映炎症活动程度,与CPH及CAH分型的病变程度划分基本一致;其纤维化分期还较好地反映了肝脏损伤的慢性程度。(2)炎症活动程度与病毒的复制状态有关。(3)CAH、CPH可以相互转化。通过对比,我们认为,Scheuer分类对慢性肝炎病变的评价较为客观、全面。
In this paper, the recent Scheuer proposed pathological grade of chronic hepatitis grading, staging criteria, compared with the domestic classification criteria, we used two criteria to observe the hospital in 10 years, 316 cases of chronic hepatitis liver biopsy, 52 cases of hepatitis B Activity and the relationship between viral replication, and analysis of the 10 cases of liver transfusion lesions. The results showed that: (1) Scheuer classification of lesions grading standards can better reflect the degree of inflammatory activity, and CPH and CAH classification of lesions is basically the same; the fibrosis stage also better reflect the degree of chronic liver injury. (2) The degree of inflammatory activity is related to the replication status of the virus. (3) CAH, CPH can transform each other. By contrast, we think, Scheuer classification of chronic hepatitis lesions evaluation is more objective and comprehensive.