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奥美拉唑(omepraole,Ome)是一种胃酸分泌抑制剂,选择性地抑制壁细胞的H~+K~+-ATP酶,从而对各种刺激因素(组胺、乙酰胆碱、胃泌素等)引起的胃酸分泌都可产生强大的剂量依赖性抑制作用。1982年首次应用于临床,对消化性溃疡、胃泌素瘤、返流性食管炎、Zollinger-Ellison综合征等疾病的疗效显著而应用日趋广泛。鉴于联合用药增加,可能会使之与其他药物的相互作用增强或减弱,现就奥美拉唑与一些常用药的
Omeprazole (omepraole, Ome) is a gastric acid secretion inhibitor that selectively inhibits parietal H ~ + K ~ + -ATPase, thereby stimulating various stimuli (histamine, acetylcholine, gastrin, etc. ) Can cause gastric acid secretion can produce a strong dose-dependent inhibition. For the first time in clinical application in 1982, the curative effect on peptic ulcer, gastrinoma, reflux esophagitis, Zollinger-Ellison syndrome and other diseases is obvious and widely used. In view of the increase in the combination of drugs, it may increase or decrease the interaction with other drugs, now omeprazole and some commonly used drugs