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本文以苯的新型生物学指标粘康酸为对照，评估了尿酚在不同苯接触浓度下的生物学监测效果。选择了三个接触不同苯浓度范围工厂内的３２６名工人为研究对象。结果三个工厂受检者接触苯浓度的范围与几何均值分别为０．２９～８．６７ｍｇ／ｍ３、３．１２～５６．８７ｍｇ／ｍ３、１７．２５～３６８．５２ｍｇ／ｍ３与２．５３ｍｇ／ｍ３、２１．０１ｍｇ／ｍ３、９４．０７ｍｇ／ｍ３。而尿酚与空气苯的相关系数分别为０．６１０７、０．７２４５、０．８０１４。相应粘康酸与空气苯的相关系数分别为０．８２１３、０．９１０７、０．８６５１。此结果说明尿酚在接触苯浓度较低时，难以反映内吸收情况。而粘康酸则能敏感地反映接触较低苯浓度环境时个体的内吸收剂量。
In this paper, a new biological indicator of benzene muconic acid as a control to assess the different concentrations of benzene in the benzene exposure to biological monitoring effect. Three workers in the factory who were exposed to different concentrations of benzene were selected as the study objects. Results The ranges and geometric mean values of exposure to benzene in the three factories were 0.29-8.67 mg / m3, 3.12-56.87 mg / m3, 17.25-3368.52 mg / m3 and 2.53 mg / Ml, 21.01 mg / m3, 94.07 mg / m3. The correlation coefficient of phenol and air phenol were 0.6107,0.7245,0.8014. The correlation coefficients between the corresponding muconic acid and air benzene were 0.8213, 0.9107 and 0.8651, respectively. This result shows that urinary phenol in contact with low concentrations of benzene, it is difficult to reflect the internal absorption. While muconic acid can sensitively reflect the internal absorbed dose of an individual exposed to a lower benzene concentration environment.