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在乳腺癌治疗中,蒽环类药物、紫杉类药物和靶向治疗药物曲妥单抗均具有心脏毒性,第三代芳香化酶抑制剂会增加冠状动脉粥样硬化性心脏病(冠心病)的风险,放疗也会引起心脏毒性。尤其以蒽环类化疗药物及其联合化疗方案的心脏毒性最为突出。因此,早期心脏毒性的检测对于预防和治疗心脏损害至关重要,心脏毒性的评价方法有多种,如心电图、心肌活检、超声心动图等,常规超声心动图是最常用的方法,超声心动图及其新技术的应用对心脏毒性的检测有重要价值。
Anthracyclines, taxanes and the targeted therapy trastuzumab are all cardiotoxic in breast cancer treatment and third-generation aromatase inhibitors increase coronary atherosclerotic heart disease (coronary heart disease ), Radiotherapy can also cause cardiotoxicity. In particular anthracycline chemotherapy and its combination of chemotherapy cardiotoxicity the most prominent. Therefore, the detection of early cardiotoxicity is very important for the prevention and treatment of heart damage. There are many ways to evaluate cardiotoxicity, such as electrocardiogram, myocardial biopsy and echocardiography. Conventional echocardiography is the most commonly used method. Echocardiography The application of its new technology is of great value to the detection of cardiotoxicity.