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目的总结胰腺癌的临床特点,探讨早期诊断的临床方法.方法采用回顾性分析的方法,对确诊的74例胰腺癌患者的临床资料进行分析.结果胰腺癌症状复杂,临床表现主要包括上腹部疼痛不适、黄疸、糖尿病症状、消瘦及纳差.B超检查阳性率为59.0%,CT平扫+增强扫描准确率达95.8%.肿瘤标志物CA199的敏感性为83.8%,CA125为37.3%.66例患者在确诊时已属于Ⅳ期,其中18例在发现远处转移灶后才找到原发病灶.20例患者接受了手术,其中根治性切除仅7例.结论提高胰腺癌的早期诊断率是改善胰腺癌预后的关键.胰腺癌早期症状不典型,对于有不明原因的上腹不适、黄疸、消瘦等症状的患者,应警惕胰腺癌,可行B超、CT等检查明确诊断.“,”Objective To summarize the clinical characteristics and to study the clinical method of early diagnosis of pancreatic cancer.Methods The clinical data of 74 patients with proven carcinoma of pancreatic were retrospectively analyzed.Results The major complaints of pancreatic cancer included abdominal pain,jaundice,symptoms of diabetes,anorexia and weight loss.The diagnostic rate of Ultrasonography and CT was 59.0% and 95.8%,seperatively the sensitivities of tumor markers CA199 was 83.8%,and CA125 was 37.3%.66 cases were stage Ⅳ cancer when diagnosed.Metastasis was found in 18 cases before the primary cancerous sites were found.20 patients received surgical treatments including radical pancreatoduodenectomy in 7 cases. Conclusions Early diagnosis is the key for improvement of its prognosis.The early symptoms of pancreatic cancer are not typical.For patients with unexplained abdominal discomfort,jaundice,or weight loss,the possibility of pancreatic cancer should be taken into consideration and ultrasonography and CT could be used.