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为再评价尿蛋白定性定量在糖尿病肾病 (DN)诊断中的价值 ,根据尿常规检查将 1 36例 DN分为尿蛋白阴性组 (41例 )和阳性组 (95例 )两组 ,比较两组间各项临床和生化指标及糖尿病其它并发症发生率的差异。结果 :两组患者血糖和糖化血红蛋白均有升高 ,并以阴性组为甚 (P分别 <0 .0 1和 <0 .0 5 ) ;高血压及糖尿病其它并发症发生率两组均较高 ,尤以阳性组为甚 (P<0 .0 5或 <0 .0 1 ) ,其中高脂血症发生率高达 40 %以上 ,两组无显著性差异 (P>0 .0 5 )。分层分析发现高血压发生率与尿蛋白有相关性 (P<0 .0 1 )。视网膜病变与尿蛋白无关。尿蛋白阴性组氮质血症发生率达 1 7.0 7%。以上提示 :尿蛋白的多少不能完全反映 DN的病程和病变严重程度 ,尿蛋白阴性不能排出 DN的诊断 ,诊断 DN应结合血糖、血脂、血压及眼底改变来综合考虑
In order to evaluate the value of qualitative and quantitative assessment of urinary protein in the diagnosis of diabetic nephropathy (DN), 136 DN patients were divided into two groups according to urinalysis: negative urine protein group (41 cases) and positive group (95 cases) Between the clinical and biochemical indicators and other complications of diabetes incidence differences. Results: The blood glucose and HbA1c in both groups were significantly higher than those in the negative group (P <0.01 and <0.05). The incidence of other complications of hypertension and diabetes was higher in both groups , Especially in the positive group (P <0.05 or <0.01). The incidence of hyperlipidemia was over 40%, with no significant difference between the two groups (P> 0.05). Stratified analysis showed that the incidence of hypertension was correlated with urinary protein (P <0.01). Retinopathy has nothing to do with urinary protein. Urinary protein negative group azotemia incidence rate of 1 7.0 7%. The above tips: the number of urinary protein can not fully reflect the course of DN and the severity of the disease, urinary protein negative can not be discharged DN diagnosis, diagnosis of DN should be combined with blood glucose, blood pressure, blood pressure and fundus changes to consider