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我国系乙型肝炎高发区,人群中乙型肝炎表面抗原血症(HBsAg携带者)的阳性率约为10％,已成为一个严重的社会问题。但是目前对其临床意义、预后与处理存在着不同的认识,现综述于下。一、HBsAg的本质与检测:HBsAg系病毒蛋白质外壳,不含核酸。用琼脂扩散技术发现HBsAg含有共同抗原决定族a(a_1、a_2、a_3)和二组彼此排斥的亚型决定族d/y和w/r,经过组合可分成10型。我国亚型分布以adw_2、adr和ayw_2为主。其他已发现的抗原决定族有q、x、f、t、n、j、g,意义
The prevalence of hepatitis B surface antigen (HBsAg carriers) in population is about 10% in our country with high incidence of hepatitis B, which has become a serious social problem. However, there is a different understanding of its clinical significance, prognosis and treatment, which are summarized below. First, the essence of HBsAg and detection: HBsAg virus protein shell, free of nucleic acid. The results of agar diffusion showed that HBsAg contained the common antigenic determinants a (a_1, a_2, a_3) and the two groups were mutually exclusive subfamily d / y and w / r, which could be divided into 10 types. Subtypes in China are mainly adw_2, adr and ayw_2. Other found antigenic determinants have q, x, f, t, n, j, g, meaning