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肥胖与脂肪肝,关系最密切作为人体物质代谢中枢和第二热量贮库的肝脏,最易因为代谢应激而发生损伤。肥胖是引起健康体检者血清转氨酶升高的常见原因,肥胖者中非酒精性脂肪性肝病(60%~90%)、非酒精性脂肪性肝炎(20%~25%),非酒精性脂肪性肝硬化(2%~8%)的患病率都很高。肥胖与脂肪肝的关系比过量饮酒与脂肪肝的关系更为密切,且肥胖可加剧酒精性肝损害的发生和发展。肥胖不仅是隐源性肝硬化、酒精性肝硬化患者并发肝细胞癌的重要危险因素,还可能影响某些肝病的治疗效果。
Obesity and fatty liver, the closest relationship As the body’s metabolic center and the second heat storage of the liver, the most vulnerable to metabolic stress damage. Obesity is a common cause of elevated serum aminotransferases in healthy individuals. Non-alcoholic fatty liver disease (60% -90%) in obese individuals, nonalcoholic steatohepatitis (20-25%), non-alcoholic fatty The prevalence of cirrhosis (2% to 8%) is high. Obesity and fatty liver than excessive drinking and fatty liver more closely, and obesity can aggravate the occurrence and development of alcoholic liver damage. Obesity is not only an important risk factor for HCC in patients with cryptogenic cirrhosis and alcoholic cirrhosis, but also may affect the therapeutic effect of some liver diseases.