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近年来,随着医学生物学的发展,已明确活性氧的毒性与许多疾病和病理有关。氧的剧烈的化学反应性,使它具有既可被利用作为强大的能源;又可产生危险的反应中间体的二面性。具有毒性的反应中间体有O_2~-、H_2O_2、·OH、H ClO~-等,统称活性氧。需氧生物细胞内存在超氧化物歧化酶(SOD),过氧化氢酶(CAT)和谷胱甘肽过氧化物酶(GSHPx)等消除活性氧的酶类。而铜(Cu)、锌(Zn)、锰(Mn)、铁(Fe)、硒(Se)等是这些酶的功能活动不可缺
In recent years, with the development of medical biology, it has been clarified that the toxicity of active oxygen is related to many diseases and pathologies. The violent chemical reactivity of oxygen gives it the potential to be exploited as a powerful source of energy as well as to create the duality of dangerous reaction intermediates. Toxic reaction intermediates O_2 ~ -, H_2O_2, · OH, H ClO ~ -, collectively referred to as reactive oxygen species. Aerobic organisms exist in the cell superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSHPx) and other enzymes to eliminate reactive oxygen species. Cu, Zn, Mn, Fe and Se are indispensable for the functional activities of these enzymes