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目的探讨风疹病毒(RV)感染与孕妇流产、死(畸)胎的关系。对160例RV感染孕妇和861例对照者进行了调查分析。方法采用胶体金标法检测RV-IgM特异性抗体。结果 RV-IgM阳性组出生缺陷、胎死宫内、流产、胎儿宫内发育迟缓发生率明显高于RV-IgM阴性组(P<0.05),差异有统计学意义。结论 RV感染与孕妇死(畸)胎和流产有关。
Objective To investigate the relationship between rubella virus (RV) infection and miscarriage and malformation in pregnant women. 160 pregnant women with RV infection and 861 controls were investigated. Methods Colloidal gold labeling was used to detect RV-IgM specific antibodies. Results The incidence of birth defects, fetal death, miscarriage and intrauterine growth retardation in RV-IgM positive group were significantly higher than those in RV-IgM negative group (P <0.05). The difference was statistically significant. Conclusion RV infection is associated with fetal death and miscarriage in pregnant women.