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目的为了解本地区实施“消峰工程”(消除山西省神经管畸形高峰)措施前后神经管畸形发病情况,探讨病因,指导预防。方法比较采取积极预防措施前后我院神经管畸形发病情况。结果 2001年1月至2008年12月我院共出生围生儿7459例,其中神经管畸形76例,共引产142例,因神经管畸形引产10例。实施消峰工程后2009年1月至2010年12月共出生围生儿2452例,其中神经管畸形1例,共引产27例,因神经管畸形引产4例。结论孕妇口服斯利安加妊娠中期B超筛查,有效降低了神经管畸形的发生率及出生率。
Objective To understand the incidence of neural tube defects before and after the implementation of “Xiaofeng Project” (eliminating the peak of neural tube defects in Shanxi Province) in this area to explore the etiology and to guide the prevention. Methods to compare the incidence of neural tube defects in our hospital before and after taking active preventive measures. Results From January 2001 to December 2008, a total of 7459 cases of perinatal children were born in our hospital, of which 76 cases of neural tube defects, a total of 142 cases of induced labor, induced by neural tube defects in 10 cases. After the implementation of peak elimination project from January 2009 to December 2010 were born in 2452 cases of perinatal children, including 1 case of neural tube defects, a total of 27 cases of induced labor, induced by neural tube defects in 4 cases. Conclusions Pregnant women received oral B-super screening in the second trimester of pregnancy, effectively reducing the incidence of neural tube defects and their birth rate.