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为确定子宫内膜刷活检在诊断子宫内膜癌中的作用进行前瞻性研究。对1997年1月～1999年12月在纽约大学医学中心就诊的101例妇女同时采用内膜刷和吸管法活检取样术。前50例患者先用吸管法,后50例患者先用内膜刷法。活检指征为不规则出血,先前活检异常或超声检查异常。术后每隔3～6月进行一次随访,或至诊刮或子宫全切术止。无1例失访。随访结束时未发现子宫内膜癌者为无恶变者。结果采用双向t检验及X~2检验。 结果:101例妇女平均随访21.3(6～32,中位数>21)月。仅1例取样不成功,无并发症。平均年龄58岁。73例绝经,平均绝经年龄61.3岁。绝经前妇女平均年龄45.7岁。65例(64.5％)因不规则阴道出血、12例(11.5％)因超声异常、13例
To determine the endometrial brush biopsy in the diagnosis of endometrial cancer in a prospective study. A total of 101 women who visited the New York University Medical Center between January 1997 and December 1999 were treated with endomyocardial brush and pipette biopsy. The first 50 patients with pipette method, after 50 patients with endometrial brush method. Biopsy indications for irregular bleeding, previous biopsy abnormalities or ultrasound abnormalities. After every 3 to 6 months for a follow-up, or curettage or hysterectomy only. No one lost to follow up. No endometrial cancer was found at the end of follow-up as non-malignant. Results using two-way t test and X ~ 2 test. Results: The average follow-up of 101 women was 21.3 (range 6 to 32, median> 21) months. Only 1 case of unsuccessful sampling, no complications. The average age is 58 years old. 73 cases of menopause, the average age of menopause 61.3 years. The average age of premenopausal women 45.7 years old. 65 cases (64.5%) due to irregular vaginal bleeding, 12 cases (11.5%) due to abnormal ultrasound, 13 cases