溢乳患者检测血PRL、FSH、LH、E_2、P值的临床意义

• 作 者: 佟慕光 俞国良 唐敖荣 沈丽君 刘世范 冯缵冲 王中兴 郑树衡 黄玉莲 沈维雄 顾锡根 颜阿林
• 机 构: 上海第二医学院附属瑞金医院,上海第二医学院附属瑞金医院,上海第二医学院附属瑞金医院,上海第二医学院附属瑞金医院,上海市计划生育研究所,上海市计划生育研究所,上海市计划生育研究所,上海市计划生育研究所,
• 出 处: 上海第二医学院学报
• 发表日期: 1985年01期
• 关键词: 溢乳 FSH LH PRL E_2 促卵泡成熟素 促黄体生成素 雌二醇(E_2) 孕酮(P) 垂体瘤

本文对38例溢乳患者分别检测血PRL、FSH、LH、E_2、P,结果表明,溢乳现象与血PRL值高低无关(p>0.05):全组患者E_2水平大多低下,但高PRL组其FSH、LH值大部低于正常,而正常PRL组则FSH、LH大多正常或偏高,两者有显著差异(P<0.01),提示高PRL时,对下丘脑分泌FSH、LH有抑制作用,临床应与卵巢性闭经所出现的雌激素水平低下相鉴别。有垂体瘤者,在眼底、视野检查未出现异常前,血PRL即呈高值,故对溢乳闭经者及时检血PRL,有助于垂体瘤的早期诊断。

The results showed that the phenomenon of galactorrhea was not related to the level of blood PRL (p> 0.05). Most of the patients had lower E_2 levels, but the levels of FSH , Most of the LH values ​​were lower than normal, while normal PRL group was normal or elevated FSH and LH, both of which were significantly different (P <0.01), suggesting that the high PRL, the hypothalamus secretion FSH, LH inhibition, Clinical should be differentiated ovarian amenorrhea low estrogen levels appear. Pituitary tumor, in the fundus, visual field examination before the abnormal, blood PRL showed high value, so timely amenorrhea were detected PRL, contribute to the early diagnosis of pituitary tumors.