Algorithms for network-based identification of differential regulators from transcriptome data： a sy

• 作 者: YU Hui MITRA Ramkrishna YANG J
• 机 构: DepartmentofBiomedicallnformatics,SchoolofBiotechnology,ShanghaiCenterforBioinformationTechnology,De
• 出 处: 中国科学：生命科学英文版
• 发表日期: 2014年11期
• 关键词: 计算算法 监管机构 蜂窝系统 转录组 数据网络 识别 评价 基础 differential regulation differential co-expres
• 基金项目: partially supported by US National Institutes of Health(R01LM011177,R03CA167695,P30CA68485,P50CA095103 and P50CA098131),Ingram Professorship Funds(to Zhao ZhongMing),The Robert J.Kleberg,Jr.and Helen

Identification of differential regulators is critical to understand the dynamics of cellular systems and molecular mechanisms of diseases.Several computational algorithms have recently been developed for this purpose by using transcriptome and network dat