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为达到国际上对减毒活疫苗生产用细胞基质的要求,我们曾将乙型脑炎(乙脑)地鼠肾细胞减毒株(SA14-14-2株)病毒在原代狗肾细胞培养内传代适应获得狗肾细胞适应株,并经全面检定证明其残余毒力和免疫原性与原地鼠肾细胞减毒株相似。为了解用该毒株制成的疫苗对人体的安全性
In order to achieve the international requirement for the cellular matrix for live attenuated vaccine production, we have infected the virus of Japanese encephalitis (JE) hamster kidney cell attenuated strain (strain SA14-14-2) in primary dog kidney cell culture Passage to adapt to get dog kidney cells, and after a comprehensive test to prove its residual virulence and immunogenicity and the original hamster kidney cell attenuated strains similar. In order to understand the vaccine made of the strain of human security