论文部分内容阅读
报道１２名受试者在静滴５％ＮａＣｌ２ｈ（每分钟０．０６ｍｌ／ｋｇ）的过程中血钠、血渗、血浆精氨酸加压素（ＡＶＰ）浓度和渴感等级的变化。结果显示，血浆ＡＶＰ浓度及渴感等级分别与血渗呈线性相关，回归方程分别为：血浆ＡＶＰ浓度（ｐＡＶＰ）－０．２４［血浆渗透压（ｐＯｓｍ）－２７４］（ｒ＝０．７２，Ｐ＜０．００１）；渴感等级（Ｔｈ）＝０．２３（ｐＯｓｍ－２７９）（ｒ＝０．６２，Ｐ＜０．００１）．两者灵敏度及阈值均较国外文献报道的结果低，认为加压素释放及渴感的渗透压阈值可能与遗传因素及生活习俗有关，ＡＶＰ分泌及渴感的渗透压调节可能存在种族差异。
Twelve subjects were reported to have changes in blood sodium, blood osmolality, plasma arginine vasopressin (AVP) concentration, and thirst level during an infusion of 5% NaCl 2 h (0.06 ml / kg per minute). The results showed that the plasma AVP concentration and thirst level were linearly correlated with the blood levels, the regression equations were: plasma AVP concentration (pAVP) -0.24 [plasma osmolality (pOsm) -274] (r = 0.72, P <0.001). Thirstiness (Th) = 0.23 (pOsm-279) (r = 0.62, P <0.001). Both sensitivity and threshold values were lower than those reported in foreign literature, and the threshold of vasopressin release and thirsty osmotic pressure may be related to genetic factors and lifestyle. There may be racial differences in the regulation of AVP secretion and thirsty osmotic pressure.